https://ntp.niehs.nih.gov/go/14718

Isophosphamide: Target Organs and Levels of Evidence for TR-032

Bioassay of Isophosphamide for Possible Carcinogenicity (CASRN 3778-73-2)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Isophosphamide
3778-73-2
09/26/1977 Intraperitoneal Injection
R: 0,6,12, M: 0,10,20 MG/KG/35 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Uterus/Cervix: (LEIOMYOSARCOMA)
  • Mammary Gland: (FIBROADENOMA)
Male Mice: Negative
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: (LYMPHOMA)