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https://ntp.niehs.nih.gov/go/14728

Toxaphene: Target Organs and Levels of Evidence for TR-037

Bioassay of Toxaphene for Possible Carcinogenicity (CASRN 8001-35-2)

Chemical (Study Title)
CASRN		Peer Review DateRoute/Exposure LevelsStudy Laboratory
Toxaphene
8001-35-2		08/31/1978Dosed-Feed
MR: 0,556,1112 (AVG), FR: 0,540,1080 (AVG), M: 0,99,198 (AVG) PPM/50 PER GROUP		Gulf South Research Institute

Levels of Evidence

Male Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Thyroid Gland Follicular Cell: ADENOMA, ADENOMA OR CARCINOMA
Female Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Thyroid Gland Follicular Cell: ADENOMA
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)