https://ntp.niehs.nih.gov/go/14738

5-Azacytidine: Target Organs and Levels of Evidence for TR-042

Bioassay of 5-Azacytidine for Possible Carcinogenicity (CASRN 320-67-2)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
5-Azacytidine
320-67-2
11/28/1977 Intraperitoneal Injection
R: 0,2.6,5.2, M: 0,2.2,4.4 MG/KG/35 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Inadequate Study
Female Rats: Inadequate Study
Male Mice: Inadequate Study
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: (LYMPHOMA OR GRANULOCYTIC SARCOMA)