4,4'-Thiodianiline: Target Organs and Levels of Evidence for TR-047
Bioassay of 4,4'-Thiodianiline for Possible Carcinogenicity (CASRN 139-65-1)
Chemical (Study Title) CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|
4,4'-Thiodianiline 139-65-1 | 01/18/1978 | Dosed-Feed R: 0,1500,3000, M: 0,2500,5000 PPM/35 PER GROUP | Southern Research Institute |
Levels of Evidence
Male Rats: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Liver:
CARCINOMA
- Intestines:
ADENOCARCINOMA
- Thyroid Gland Follicular Cell:
CARCINOMA
- Zymbal Gland:
SQUAMOUS CELL PAPILLOMA OR CARCINOMA
|
Female Rats: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Thyroid Gland Follicular Cell:
CARCINOMA
- Zymbal Gland:
SQUAMOUS CELL PAPILLOMA OR CARCINOMA
- Uterus/Cervix:
ADENOCARCINOMA
|
Male Mice: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Liver:
CARCINOMA
- Thyroid Gland Follicular Cell:
CARCINOMA
|
Female Mice: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Liver:
CARCINOMA
- Thyroid Gland Follicular Cell:
ADENOMA, CARCINOMA, ADENOMA OR CARCINOMA
|