https://ntp.niehs.nih.gov/go/14762

1,2-Dichloroethane: Target Organs and Levels of Evidence for TR-055

Bioassay of 1,2-Dichloroethane for Possible Carcinogenicity (CASRN 107-06-2)

Chemical (Study Title)
CASRN		 Peer Review Date Route/Exposure Levels Study Laboratory
1,2-Dichloroethane
107-06-2		 03/06/1978 Gavage
R: 0,47,95 (AVG), MM: 0,97,195 (AVG), FM: 0,149,299 (AVG) MG/KG/50 PER GROUP		 Hazleton, Vienna

Levels of Evidence

Male Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL CARCINOMA)
  • Vascular System (Unspecified): (HEMANGIOSARCOMA)
  • Subcutaneous Tissue: (FIBROMA)
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Mammary Gland: (ADENOCARCINOMA)
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA)
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA)
  • Mammary Gland: (ADENOCARCINOMA)
  • Uterus/Cervix: (POLYP, SARCOMA)