tris(Aziridinyl)-phosphine sulfide (Thio-TEPA): Target Organs and Levels of Evidence for TR-058
Bioassay of Thio-TEPA for Possible Carcinogenicity (CASRN 52-24-4)
| Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|
| tris(Aziridinyl)-phosphine sulfide (thio-tepa) 52-24-4 |
04/26/1978 | Intraperitoneal Injection R: 0,.7,1.4,2.8, M: 0,1.15,2.3 MG/KG/35 PER GROUP |
Southern Research Institute |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|