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Phenesterin: Target Organs and Levels of Evidence for TR-060

Bioassay of Phenesterin for Possible Carcinogenicity (CASRN 3546-10-9)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
Phenesterin 3546-10-9	03/06/1978	Gavage R: 0,5,10, M: 0,15,30 MG/KG/15 PER GROUP	Southern Research Institute

Levels of Evidence

Male Rats: Negative

Female Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Mammary Gland: (ADENOCARCINOMA)

Male Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Lung: (ALVEOLAR/BRONCHIOLAR CARCINOMA) Hematopoietic System: (LYMPHOMA) Heart: (SARCOMA)

Female Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Lung: (ALVEOLAR/BRONCHIOLAR CARCINOMA) Hematopoietic System: (LYMPHOMA) Heart: (SARCOMA)