https://ntp.niehs.nih.gov/go/14772

Phenesterin: Target Organs and Levels of Evidence for TR-060

Bioassay of Phenesterin for Possible Carcinogenicity (CASRN 3546-10-9)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Phenesterin
3546-10-9
03/06/1978 Gavage
R: 0,5,10, M: 0,15,30 MG/KG/15 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Mammary Gland: (ADENOCARCINOMA)
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Lung: (ALVEOLAR/BRONCHIOLAR CARCINOMA)
  • Hematopoietic System: (LYMPHOMA)
  • Heart: (SARCOMA)
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Lung: (ALVEOLAR/BRONCHIOLAR CARCINOMA)
  • Hematopoietic System: (LYMPHOMA)
  • Heart: (SARCOMA)