4-Chloro-o-phenylenediamine: Target Organs and Levels of Evidence for TR-063
Bioassay of 4-Chloro-o-phenylenediamine for Possible Carcinogenicity (CASRN 95-83-0)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
4-Chloro-o-phenylenediamine
95-83-0 | 03/06/1978 | Dosed-Feed
R: 0,.5,1.0 (AVG), M: 0,.7,1.4 (AVG) %DIET/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Urinary Bladder:
(TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
- Forestomach:
(SQUAMOUS CELL PAPILLOMA OR SQUAMOUS CELL CARCINOMA)
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Urinary Bladder:
(TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
- Forestomach:
(SQUAMOUS CELL PAPILLOMA OR SQUAMOUS CELL CARCINOMA)
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | |
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | |
