tris(2,3-Dibromopropyl) phosphate: Target Organs and Levels of Evidence for TR-076
Bioassay of Tris (2,3-Dibromopropyl) Phosphate for Possible Carcinogenicity (CASRN 126-72-7)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
tris(2,3-Dibromopropyl) phosphate
126-72-7 | 03/06/1978 | Dosed-Feed
R: 0,50,100, M: 0,500,1000 PPM/55 PER GROUP | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Kidney Tubular Cell:
ADENOMA, ADENOMA OR ADENOCARCINOMA
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Kidney Tubular Cell:
ADENOMA
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Kidney Tubular Cell:
ADENOMA OR ADENOCARCINOMA
- Forestomach:
(SQUAMOUS CELL PAPILLOMA, SQUAMOUS CELL PAPILLOMA OR CARCINOMA)
- Lung:
(ALVEOLAR/BRONCHIOLAR ADENOMA, ALVEOLAR/BRONCHIOLAR CARCINOMA)
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
(SQUAMOUS CELL PAPILLOMA, SQUAMOUS CELL CARCINOMA)
- Liver:
(ADENOMA, CARCINOMA)
- Lung:
(ALVEOLAR/BRONCHIOLAR ADENOMA, ALVEOLAR/BRONCHIOLAR ADENOMA OR CARCINOMA)
|
