https://ntp.niehs.nih.gov/go/8238

ICRF-159: Target Organs and Levels of Evidence for TR-078

Bioassay of ICRF-159 for Possible Carcinogenicity (CASRN 21416-87-5)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
ICRF-159
21416-87-5
03/07/1978 Intraperitoneal Injection
R: 0,48,96, M: 0,40,80 MG/KG/35 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Uterus/Cervix: (ADENOCARCINOMA)
Male Mice: Negative
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: (LYMPHOMA)