1,4-Dioxane: Target Organs and Levels of Evidence for TR-080
Bioassay of 1,4-Dioxane for Possible Carcinogenicity (CASRN 123-91-1)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
1,4-Dioxane
123-91-1 | 03/07/1978 | Dosed-Water
0,0.5,1.0 %/70R - 100M PER GROUP | IIT Research Institute |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Nasal Cavity:
(SQUAMOUS CELL CARCINOMA)
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Liver:
(ADENOMA)
- Nasal Cavity:
(SQUAMOUS CELL CARCINOMA)
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | |
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | |
