2,4-Diaminoanisole sulfate: Target Organs and Levels of Evidence for TR-084
Bioassay of 2,4-Diaminoanisole Sulfate for Possible Carcinogenicity (CASRN 615-05-4)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
2,4-Diaminoanisole sulfate
39156-41-7 | 03/06/1978 | Dosed-Feed
R: 0,.12,.5 (AVG), M: 0,.12,.24 %/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Thyroid Gland C-Cell:
ADENOMA OR CARCINOMA
- Thyroid Gland Follicular Cell:
ADENOMA OR CARCINOMA
- Skin:
(SQUAMOUS CELL CARCINOMA OR BASAL CELL CARCINOMA OR SEBACEOUS ADENOCARCINOMA)
- Zymbal Gland:
(SQUAMOUS CELL CARCINOMA OR SEBACEOUS ADENOCARCINOMA)
- Preputial Gland:
(ADENOMA OR CARCINOMA)
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Thyroid Gland Follicular Cell:
ADENOMA OR CARCINOMA
- Zymbal Gland:
(SEBACEOUS ADENOCARCINOMA)
- Clitoral Gland:
(ADENOMA OR CARCINOMA)
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Thyroid Gland Follicular Cell:
ADENOMA
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Thyroid Gland Follicular Cell:
ADENOMA OR CARCINOMA
|
