1,2-Dibromoethane: Target Organs and Levels of Evidence for TR-086
Bioassay of 1,2-Dibromoethane for Possible Carcinogenicity (CASRN 106-93-4)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
1,2-Dibromoethane
106-93-4 | 04/26/1978 | Gavage
MR: 0,38,41 (AVG), FR: 0,37,39 (AVG), M: 0,62,107 MG/KG/50 PER GROUP | Hazleton, Vienna |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
SQUAMOUS CELL CARCINOMA
- Vascular System (Unspecified):
HEMANGIOSARCOMA
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
(SQUAMOUS CELL CARCINOMA)
- Liver:
(CARCINOMA)
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
(SQUAMOUS CELL CARCINOMA)
- Lung:
(ALVEOLAR/BRONCHIOLAR ADENOMA)
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
(SQUAMOUS CELL CARCINOMA)
- Lung:
(ALVEOLAR/BRONCHIOLAR ADENOMA)
|
