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o-Anisidine hydrochloride: Target Organs and Levels of Evidence for TR-089

Bioassay of o-Anisidine Hydrochloride for Possible Carcinogenicity (CASRN 134-29-2)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
o-Anisidine hydrochloride 134-29-2	04/26/1978	Dosed-Feed R: 0,5000,10000, M: 0,2500,5000 PPM/55 PER GROUP	T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) Kidney Transitional Cell: CARCINOMA Thyroid Gland Follicular Cell: ADENOMA OR CARCINOMA

Female Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)

Male Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)

Female Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)