https://ntp.niehs.nih.gov/go/9597

o-Anisidine hydrochloride: Target Organs and Levels of Evidence for TR-089

Bioassay of o-Anisidine Hydrochloride for Possible Carcinogenicity (CASRN 134-29-2)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
o-Anisidine hydrochloride
134-29-2
04/26/1978 Dosed-Feed
R: 0,5000,10000, M: 0,2500,5000 PPM/55 PER GROUP
T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
  • Kidney Transitional Cell: CARCINOMA
  • Thyroid Gland Follicular Cell: ADENOMA OR CARCINOMA
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)