o-Anisidine hydrochloride: Target Organs and Levels of Evidence for TR-089
Bioassay of o-Anisidine Hydrochloride for Possible Carcinogenicity (CASRN 134-29-2)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
o-Anisidine hydrochloride
134-29-2 | 04/26/1978 | Dosed-Feed
R: 0,5000,10000, M: 0,2500,5000 PPM/55 PER GROUP | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Urinary Bladder:
(TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
- Kidney Transitional Cell:
CARCINOMA
- Thyroid Gland Follicular Cell:
ADENOMA OR CARCINOMA
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Urinary Bladder:
(TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Urinary Bladder:
(TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Urinary Bladder:
(TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA)
|
