https://ntp.niehs.nih.gov/go/9609

3-Chloromethylpyridine hydrochloride: Target Organs and Levels of Evidence for TR-095

Bioassay of 3-(Chloromethyl)pyridine Hydrochloride for Possible Carcinogenicity (CASRN 6959-48-4)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
3-Chloromethylpyridine hydrochloride
6959-48-4
10/25/1978 Gavage
R: 0,75,150, M: 0,100,200 MG/KG/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL PAPILLOMA OR CARCINOMA)
Female Rats: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL CARCINOMA)
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL PAPILLOMA OR CARCINOMA)
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: (SQUAMOUS CELL PAPILLOMA OR CARCINOMA)