3-Chloromethylpyridine hydrochloride: Target Organs and Levels of Evidence for TR-095
Bioassay of 3-(Chloromethyl)pyridine Hydrochloride for Possible Carcinogenicity (CASRN 6959-48-4)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
3-Chloromethylpyridine hydrochloride
6959-48-4 | 10/25/1978 | Gavage
R: 0,75,150, M: 0,100,200 MG/KG/50 PER GROUP | Litton Bionetics, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
(SQUAMOUS CELL PAPILLOMA OR CARCINOMA)
|
Female Rats: Equivocal
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
(SQUAMOUS CELL CARCINOMA)
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
(SQUAMOUS CELL PAPILLOMA OR CARCINOMA)
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Forestomach:
(SQUAMOUS CELL PAPILLOMA OR CARCINOMA)
|
