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Phenazopyridine hydrochloride: Target Organs and Levels of Evidence for TR-099

Bioassay of Phenazopyridine Hydrochloride for Possible Carcinogenicity (CASRN 136-40-3)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
Phenazopyridine hydrochloride 136-40-3	04/26/1978	Dosed-Feed R: 0,3700,7500, M: 0,600,1200 PPM/35 PER GROUP	Southern Research Institute

Levels of Evidence

Male Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Intestines: (ADENOCARCINOMA)

Female Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Intestines: (ADENOCARCINOMA)

Male Mice: Negative

Female Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Liver: (ADENOMA, CARCINOMA)