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https://ntp.niehs.nih.gov/go/9617

Phenazopyridine hydrochloride: Target Organs and Levels of Evidence for TR-099

Bioassay of Phenazopyridine Hydrochloride for Possible Carcinogenicity (CASRN 136-40-3)

Chemical (Study Title)
CASRN		Peer Review DateRoute/Exposure LevelsStudy Laboratory
Phenazopyridine hydrochloride
136-40-3		04/26/1978Dosed-Feed
R: 0,3700,7500, M: 0,600,1200 PPM/35 PER GROUP		Southern Research Institute

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Intestines: (ADENOCARCINOMA)
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Intestines: (ADENOCARCINOMA)
Male Mice: Negative
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (ADENOMA, CARCINOMA)