Cupferron: Target Organs and Levels of Evidence for TR-100
Bioassay of Cupferron for Possible Carcinogenicity (CASRN 135-20-6)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
Cupferron
135-20-6 | 06/29/1978 | Dosed-Feed
R: 0,.15,.30 M: 0,.2,.4 %/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Vascular System (Unspecified):
HEMANGIOSARCOMA
- Liver:
CARCINOMA
- Forestomach:
SQUAMOUS CELL CARCINOMA
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Vascular System (Unspecified):
HEMANGIOSARCOMA
- Liver:
CARCINOMA
- Forestomach:
SQUAMOUS CELL CARCINOMA
- Zymbal Gland:
CARCINOMA
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Vascular System (Unspecified):
HEMANGIOSARCOMA
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Liver:
CARCINOMA
- Zymbal Gland:
CARCINOMA
- Vascular System (Unspecified):
HEMANGIOMA OR HEMANGIOSARCOMA
- Harderian Gland:
ADENOMA
|
