C.I. Direct Black 38: Target Organs and Levels of Evidence for TR-108
13-Week Subchronic Toxicity Studies of Direct Blue 6, Direct Black 38, and Direct Brown 95 Dyes
| Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|
| C.I. Direct black 38 1937-37-7 |
03/06/1978 | Dosed-Feed R: 0,190,375,750,1500,3000, M: 0,750,1500,3000,6000,12500 PPM/10 PER GROUP |
Battelle Columbus Laboratory |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
| Chemical (Study Title) CASRN |
Peer Review Date | Primary Uses | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|---|
| C.I. Direct blue 6 2602-46-2 |
03/06/1978 | Dye for textiles, leather, ink; biological and wood stains; hair dyes (formerly used) | Dosed-Feed R: 0, 750, 1500, 2000, 6000, OR 12500 PPM M: 0, 190, 375, 750, 1500, OR 3000 PPM |
Battelle Columbus Laboratory |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
| Chemical (Study Title) CASRN |
Peer Review Date | Primary Uses | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|---|
| C.I. Direct brown 95 16071-86-6 |
03/06/1978 | Dye for textiles, leather, plastics, paper | Dosed-Feed R: 0,190,375,750,1500,3000, MM: 0,750,1500,3000,6000,12500, FM: 0,375,750,1500,3000,6000 PPM/10 PER GROUP |
Battelle Columbus Laboratory |
Levels of Evidence
Male Rats: Negative
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|