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https://ntp.niehs.nih.gov/go/10955

1-Amino-2-methylanthraquinone: Target Organs and Levels of Evidence for TR-111

Bioassay of 1-Amino-2-methylanthraquinone for Possible Carcinogenicity (CASRN 82-28-0)

Chemical (Study Title)
CASRN
Peer Review DateRoute/Exposure LevelsStudy Laboratory
1-Amino-2-methylanthraquinone
82-28-0
08/31/1978Dosed-Feed
R: 0,.10,.20 (AVG), M: 0,0.6 (AVG) %/50 PER GROUP
T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE, CARCINOMA)
  • Kidney Tubular Cell: ADENOMA OR ADENOCARCINOMA
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE, CARCINOMA)
Male Mice: Negative
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE OR CARCINOMA)