5-Nitroacenaphthene: Target Organs and Levels of Evidence for TR-118
Bioassay of 5-Nitroacenaphthene for Possible Carcinogenicity (CASRN 602-87-9)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
5-Nitroacenaphthene
602-87-9 | 06/29/1978 | Dosed-Feed
R: 0,.12,.24, MM: 0,.06,.12 (AVG), FM: 0,.05,.12 (AVG) %/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Zymbal Gland:
(CARCINOMA)
- Lung:
(ALVEOLAR/BRONCHIOLAR ADENOMA OR CARCINOMA)
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Zymbal Gland:
(CARCINOMA)
- Lung:
(ALVEOLAR/BRONCHIOLAR ADENOMA OR CARCINOMA)
- Mammary Gland:
(ADENOCARCINOMA)
- Clitoral Gland:
(CARCINOMA)
|
Male Mice: Negative
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Liver:
(CARCINOMA)
- Ovary:
(TUBULAR CELL ADENOMA OR GRANULOSA CELL TUMOR OR LUTEOMA)
|
