Skip to Main Navigation
Skip to Page Content

COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/13431

5-Nitro-o-anisidine: Target Organs and Levels of Evidence for TR-127

Bioassay of 5-Nitro-o-anisidine for Possible Carcinogenicity (CASRN 99-59-2)

Chemical (Study Title)
CASRN
Peer Review DateRoute/Exposure LevelsStudy Laboratory
5-Nitro-o-anisidine
99-59-2
06/29/1978Dosed-Feed
R: 0,.4,.8, M: 0,.4,.8,1.6 %/50 PER GROUP
T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Skin: (TRICHOEPITHELIOMA, SEBACEOUS ADENOMA, BASAL CELL CARCINOMA, SQUAMOUS CELL CARCINOMA, ADENOCARCINOMA)
  • Zymbal Gland: (CARCINOMA)
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Clitoral Gland: (ADENOMA, CARCINOMA)
  • Zymbal Gland: (CARCINOMA)
Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)