Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/6185

Nithiazide: Target Organs and Levels of Evidence for TR-146

Bioassay of Nithiazide for Possible Carcinogenicity (CASRN 139-94-6)

Chemical (Study Title)
CASRN		Peer Review DateRoute/Exposure LevelsStudy Laboratory
Nithiazide
139-94-6		10/25/1978Dosed-Feed
R: 0,625,1250, M: 0,2500,5000 PPM/50 PER GROUP		Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Mammary Gland: (FIBROADENOMA OR CYSTADENOMA)
  • Skin: (FIBROADENOMA OR CYSTADENOMA)
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (ADENOMA OR CARCINOMA)
Female Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (ADENOMA OR CARCINOMA)