Nithiazide: Target Organs and Levels of Evidence for TR-146
Bioassay of Nithiazide for Possible Carcinogenicity (CASRN 139-94-6)
Chemical (Study Title) CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|
Nithiazide 139-94-6 | 10/25/1978 | Dosed-Feed R: 0,625,1250, M: 0,2500,5000 PPM/50 PER GROUP | Litton Bionetics, Inc. |
Levels of Evidence
Male Rats: Negative
Female Rats: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Mammary Gland:
(FIBROADENOMA OR CYSTADENOMA)
- Skin:
(FIBROADENOMA OR CYSTADENOMA)
|
Male Mice: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Liver:
(ADENOMA OR CARCINOMA)
|
Female Mice: Equivocal
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Liver:
(ADENOMA OR CARCINOMA)
|