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N,N'-Diethylthiourea: Target Organs and Levels of Evidence for TR-149

Bioassay of N,N'-Diethylthiourea for Possible Carcinogenicity (CASRN 105-55-5)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
N,N'-Diethylthiourea 105-55-5	08/31/1978	Dosed-Feed R: 0,125,250, M: 0,250,500 PPM/50 PER GROUP	Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Thyroid Gland Follicular Cell: CARCINOMA

Female Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Thyroid Gland Follicular Cell: ADENOMA OR CARCINOMA

N,N'-Diethylthiourea: Target Organs and Levels of Evidence for TR-149

Bioassay of N,N'-Diethylthiourea for Possible Carcinogenicity (CASRN 105-55-5)

Levels of Evidence

Male Rats: Positive

Female Rats: Positive

Male Mice: Negative

Female Mice: Negative