https://ntp.niehs.nih.gov/go/6191

N,N'-Diethylthiourea: Target Organs and Levels of Evidence for TR-149

Bioassay of N,N'-Diethylthiourea for Possible Carcinogenicity (CASRN 105-55-5)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
N,N'-Diethylthiourea
105-55-5
08/31/1978 Dosed-Feed
R: 0,125,250, M: 0,250,500 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Thyroid Gland Follicular Cell: CARCINOMA
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Thyroid Gland Follicular Cell: ADENOMA OR CARCINOMA
Male Mice: Negative
Female Mice: Negative