https://ntp.niehs.nih.gov/go/6213

2,4,5-Trimethylaniline: Target Organs and Levels of Evidence for TR-160

Bioassay of 2,4,5-Trimethylaniline for Possible Carcinogenicity (CASRN 137-17-7)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
2,4,5-Trimethylaniline
137-17-7
12/13/1978 Dosed-Feed
R: 0,200,800, M: 0,50,100 PPM/50 PER GROUP
Frederick Cancer Research Facility

Levels of Evidence

Male Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE, CARCINOMA)
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE, CARCINOMA)
  • Lung: (ALVEOLAR/BRONCHIOLAR CARCINOMA)
Male Mice: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)