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2,4,5-Trimethylaniline: Target Organs and Levels of Evidence for TR-160

Bioassay of 2,4,5-Trimethylaniline for Possible Carcinogenicity (CASRN 137-17-7)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
2,4,5-Trimethylaniline 137-17-7	12/13/1978	Dosed-Feed R: 0,200,800, M: 0,50,100 PPM/50 PER GROUP	Frederick Cancer Research Facility

Levels of Evidence

Male Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Liver: (NEOPLASTIC NODULE, CARCINOMA)

Female Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Liver: (NEOPLASTIC NODULE, CARCINOMA) Lung: (ALVEOLAR/BRONCHIOLAR CARCINOMA)

Male Mice: Equivocal

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Liver: (CARCINOMA)

Female Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Liver: (CARCINOMA)