2,4,5-Trimethylaniline: Target Organs and Levels of Evidence for TR-160
Bioassay of 2,4,5-Trimethylaniline for Possible Carcinogenicity (CASRN 137-17-7)
Chemical (Study Title) CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|
2,4,5-Trimethylaniline 137-17-7 | 12/13/1978 | Dosed-Feed R: 0,200,800, M: 0,50,100 PPM/50 PER GROUP | Frederick Cancer Research Facility |
Levels of Evidence
Male Rats: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Liver:
(NEOPLASTIC NODULE, CARCINOMA)
|
Female Rats: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Liver:
(NEOPLASTIC NODULE, CARCINOMA)
- Lung:
(ALVEOLAR/BRONCHIOLAR CARCINOMA)
|
Male Mice: Equivocal
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | |
Female Mice: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | |