2,4-Diaminotoluene (2,4-toluene diamine): Target Organs and Levels of Evidence for TR-162
Bioassay of 2,4-Diaminotoluene for Possible Carcinogenicity (CASRN 95-80-7)
Chemical (Study Title) CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|
2,4-Diaminotoluene (2,4-toluene diamine) 95-80-7 | 12/13/1978 | Dosed-Feed MR: 0,79,176 (AVG), FR: 0,79,171 (AVG), M: 0,100,200 PPM/50 PER GROUP | Frederick Cancer Research Facility |
Levels of Evidence
Male Rats: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Liver:
(NEOPLASTIC NODULE, CARCINOMA)
|
Female Rats: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | - Mammary Gland:
(ADENOMA, CARCINOMA)
- Liver:
(NEOPLASTIC NODULE, CARCINOMA)
|
Male Mice: Negative
Female Mice: Positive
Type | Organ/Tissue (Lesion) |
---|
Neoplastic Lesions | |
May Have Been Related | - Hematopoietic System:
(LYMPHOMA)
|