4,4'-Methylenebis(N,N-dimethyl)benzenamine: Target Organs and Levels of Evidence for TR-186
Bioassay of 4,4'-Methylenebis-(N,N-dimethyl)benzeneamine for Possible Carcinogenicity (CASRN 101-61-1)
| Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|
| 4,4'-Methylenebis(N,N-dimethyl)benzenamine 101-61-1 |
10/25/1978 | Dosed-Feed R: 0,375,750, M: 0,1250,2500 PPM/50 PER GROUP |
Litton Bionetics, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Male Mice: Equivocal
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|