https://ntp.niehs.nih.gov/go/8419

p-Chloroaniline: Target Organs and Levels of Evidence for TR-189

Bioassay of p-Chloroaniline for Possible Carcinogenicity (CASRN 106-47-8)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
p-Chloroaniline
106-47-8
10/25/1978 Dosed-Feed
R: 0,250,500, M: 0,2500,5000 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Spleen: SARCOMA
Female Rats: Negative
Male Mice: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Vascular System (Unspecified): HEMANGIOSARCOMA
Female Mice: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Vascular System (Unspecified): HEMANGIOSARCOMA