Reserpine: Target Organs and Levels of Evidence for TR-193
Bioassay of Reserpine for Possible Carcinogenicity (CASRN 50-55-5)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
Reserpine
50-55-5 | 05/01/1979 | Dosed-Feed
0,5,10 PPM/50 PER GROUP | Southern Research Institute |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Adrenal Gland Medulla:
PHEOCHROMOCYTOMA
|
Female Rats: Negative
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Seminal Vesicle:
(CARCINOMA)
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Mammary Gland:
(FIBROADENOMA, ADENOCARCINOMA, ADENOSQUAMOUS CARCINOMA)
|
