1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin: Target Organs and Levels of Evidence for TR-198
Bioassay of a Mixture of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin and 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (Gavage) for Possible Carcinogenicity (CASRN 57653-85-7, CASRN 19408-74-3)
| Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|
| 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin 57653-85-7 |
02/15/1980 | Gavage R&MM: 0,1.25,2.5,5.0, FM: 0,2.5,5.0,10.0 UG/KG/50 PER GROUP |
IIT Research Institute |
Levels of Evidence
Male Rats: Equivocal
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|