https://ntp.niehs.nih.gov/go/10316

2,3,7,8-Tetrachlorodibenzo-p-dioxin: Target Organs and Levels of Evidence for TR-201

Carcinogenesis Bioassay of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CASRN 1746-01-6) in Swiss-Webster Mice (Dermal Study)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
2,3,7,8-Tetrachlorodibenzo-p-dioxin
1746-01-6
06/27/1980 Topical Application
FM: 0,.005, MM: 0,.001 UG/60 PER GROUP
IIT Research Institute

Levels of Evidence

Male Mice: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Subcutaneous Tissue: FIBROSARCOMA 3/42 6/28
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Subcutaneous Tissue: FIBROSARCOMA 2/41 8/27