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2,3,7,8-Tetrachlorodibenzo-p-dioxin: Target Organs and Levels of Evidence for TR-201

Carcinogenesis Bioassay of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CASRN 1746-01-6) in Swiss-Webster Mice (Dermal Study)

Chemical (Study Title)
Peer Review DateRoute/Exposure LevelsStudy Laboratory
06/27/1980Topical Application
FM: 0,.005, MM: 0,.001 UG/60 PER GROUP
IIT Research Institute

Levels of Evidence

Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Subcutaneous Tissue: FIBROSARCOMA 3/42 6/28
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Subcutaneous Tissue: FIBROSARCOMA 2/41 8/27