4,4'-Oxydianiline: Target Organs and Levels of Evidence for TR-205
Bioassay of 4,4'-Oxydianiline for Possible Carcinogenicity (CASRN 101-80-4)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
4,4'-Oxydianiline
101-80-4 | 02/15/1980 | Dosed-Feed
R: 0,200,400,500, M: 0,150,300,800 PPM/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Liver:
(NEOPLASTIC NODULE, CARCINOMA)
- Thyroid Gland Follicular Cell:
ADENOMA OR CARCINOMA
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Liver:
(NEOPLASTIC NODULE, CARCINOMA)
- Thyroid Gland Follicular Cell:
ADENOMA OR CARCINOMA
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Harderian Gland:
(ADENOMA)
- Liver:
(ADENOMA OR CARCINOMA)
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Harderian Gland:
(ADENOMA)
- Liver:
(CARCINOMA)
- Thyroid Gland Follicular Cell:
ADENOMA
|
