https://ntp.niehs.nih.gov/go/9792

Bisphenol A: Target Organs and Levels of Evidence for TR-215

Carcinogenesis Bioassay of Bisphenol A (CASRN 80-05-7) in F344 Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title)
CASRN		 Peer Review Date Route/Exposure Levels Study Laboratory
Bisphenol A
80-05-7		 10/15/1980 Dosed-Feed
R: 0,1000,2000, FM: 0,5000,10000, MM: 0,1000,5000 PPM/50 PER GROUP		 Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: LEUKEMIA 13/50 12/50 23/50
  • Testis: INTERSTITIAL CELL 35/49 9/50 46/49
Female Rats: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: LEUKEMIA 7/50 13/50 12/50
Male Mice: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: LYMPHOMA 2/49 9/50 5/50
Female Mice: Negative