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Bisphenol A: Target Organs and Levels of Evidence for TR-215

Carcinogenesis Bioassay of Bisphenol A (CASRN 80-05-7) in F344 Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
Bisphenol A 80-05-7	10/15/1980	Dosed-Feed R: 0,1000,2000, FM: 0,5000,10000, MM: 0,1000,5000 PPM/50 PER GROUP	Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Equivocal

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Hematopoietic System: LEUKEMIA 13/50 12/50 23/50 Testis: INTERSTITIAL CELL 35/49 9/50 46/49

Female Rats: Equivocal

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Hematopoietic System: LEUKEMIA 7/50 13/50 12/50

Male Mice: Equivocal

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Hematopoietic System: LYMPHOMA 2/49 9/50 5/50