Bisphenol A: Target Organs and Levels of Evidence for TR-215
Carcinogenesis Bioassay of Bisphenol A (CASRN 80-05-7) in F344 Rats and B6C3F1 Mice (Feed Study)
Chemical (Study Title)
CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|
Bisphenol A
80-05-7 | 10/15/1980 | Dosed-Feed
R: 0,1000,2000, FM: 0,5000,10000, MM: 0,1000,5000 PPM/50 PER GROUP | Litton Bionetics, Inc. |
Levels of Evidence
Male Rats: Equivocal
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Hematopoietic System:
LEUKEMIA 13/50 12/50 23/50
- Testis:
INTERSTITIAL CELL 35/49 9/50 46/49
|
Female Rats: Equivocal
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Hematopoietic System:
LEUKEMIA 7/50 13/50 12/50
|
Male Mice: Equivocal
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Hematopoietic System:
LYMPHOMA 2/49 9/50 5/50
|
Female Mice: Negative
