Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

C.I. Disperse Yellow 3: Target Organs and Levels of Evidence for TR-222

Carcinogenesis Bioassay of Disperse Yellow 3 (CASRN 2832-40-8) in F344 Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title)
Peer Review DateRoute/Exposure LevelsStudy Laboratory
C.I. Disperse yellow 3
R: 0,5000,10000, M: 0,2500,5000 PPM/50 PER GROUP
Battelle Columbus Laboratory

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: NEOPLASTIC NODULE 1/49 15/50 10/50
May Have Been Related
  • Glandular Stomach: ADENOMA 0/49 1/50 0/50; ADENOCARCINOMA 0/49 1/501/50; SARCOMA 0/49 0/50 1/50
  • Forestomach: SQUAMOUS CELL PAPILLOMA 0/49 1/50 0/50; FIBROSARCOMA 0/49 1/50 0/50; SARCOMA 0/49 0/50 1/50
Female Rats: Negative
Male Mice: Negative
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: ADENOMA 0/50 6/50 12/50
May Have Been Related
  • Hematopoietic System: LYMPHOMA 10/50 16/50 19/50