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D&C Red No. 9: Target Organs and Levels of Evidence for TR-225

Carcinogenesis Bioassay of D & C Red No. 9 (CASRN 5160-02-1) in F344 Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
D & C red no. 9 5160-02-1	02/18/1981	Dosed-Feed R: 0,1000,3000, M: 0,1000,2000 PPM/50 PER GROUP	Battelle Columbus Laboratory

Levels of Evidence

Male Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Spleen: SARCOMA 0/50 0/50 26/48 Liver: NEOPLASTIC NODULE 0/50 6/50 7/49

Female Rats: Equivocal

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Liver: NEOPLASTIC NODULE 1/50 1/50 5/50

D&C Red No. 9: Target Organs and Levels of Evidence for TR-225

Carcinogenesis Bioassay of D & C Red No. 9 (CASRN 5160-02-1) in F344 Rats and B6C3F1 Mice (Feed Study)

Levels of Evidence

Male Rats: Positive

Female Rats: Equivocal

Male Mice: Negative

Female Mice: Negative