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2-Biphenylamine hydrochloride: Target Organs and Levels of Evidence for TR-233

Carcinogenesis Bioassay of 2-Biphenylamine Hydrochloride (CASRN 2185-92-4) in F344/N Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
2-Biphenylamine hydrochloride 2185-92-4	06/23/1981	Dosed-Feed 0,1000,3000 PPM/50 PER GROUP	T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Negative

Female Rats: Negative

Male Mice: Equivocal

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Vascular System (Unspecified): HEMANGIOSARCOMA 0/50 2/50 3/50

Female Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Vascular System (Unspecified): HEMANGIOSARCOMA 0/49 1/50 7/50