https://ntp.niehs.nih.gov/go/7146

Zearalenone: Target Organs and Levels of Evidence for TR-235

Carcinogenesis Bioassay of Zearalenone (CASRN 17924-92-4) in F344/N Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Zearalenone
17924-92-4
12/16/1981 Dosed-Feed
R: 0, 25, OR 50 PPM M: 0, 50, OR 100 PPM
Southern Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Pituitary Gland: ADENOMA 0/40 4/45 6/44
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Pituitary Gland: ADENOMA 3/46 2/43 13/42
  • Liver: ADENOMA 0/50 2/49 7/49