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Allyl isovalerate: Target Organs and Levels of Evidence for TR-253

Carcinogenesis Studies of Allyl Isovalerate (CASRN 2835-39-4) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
Allyl isovalerate 2835-39-4	09/22/1982	Gavage 0,31,62 MG/KG/50 PER GROUP	Southern Research Institute

Levels of Evidence

Male Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Hematopoietic System: LEUKEMIA 1/50 4/50 7/50

Female Rats: Negative

Male Mice: Negative

Female Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Hematopoietic System: LYMPHOMA 11/50 11/50 18/50