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Target Organs and Levels of Evidence for TR-261

Toxicology and Carcinogenesis Studies of Chlorobenzene (CASRN 108-90-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
Peer Review Date Route/Exposure Levels Study Laboratory
02/28/1983 Gavage
R&FM: 0,60,120, MM: 0,30,60 MG/KG/50 PER GROUP
Battelle Columbus Laboratory

Levels of Evidence

Male Rats: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: NEOPLASTIC NODULE 4/50 2/50 4/49 8/49
Female Rats: Negative
Male Mice: Negative
Female Mice: Negative