https://ntp.niehs.nih.gov/go/7602

Target Organs and Levels of Evidence for TR-266

Toxicology and Carcinogenesis Studies of Monuron (CASRN 150-68-5) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Chemical (Study Title)
CASRN		 Peer Review Date Route/Exposure Levels Study Laboratory
Monuron
150-68-5		 06/29/1983 Dosed-Feed
R: 0,750,1500, M: 0,5000,10000 PPM/50 PER GROUP		 T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Clear Evidence
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Kidney Tubular Cell: ADENOMA 0/50 2/50 7/50 OR ADENOCARCINOMA 0/50 1/50 8/50
  • Liver: NEOPLASTIC NODULE 1/50 6/49 7/50 OR CARCINOMA 0/50 1/49 3/50 COMBINED 1/50 6/49 9/50
Non-Neoplastic Lesions
  • KIDNEY: CYTOMEGALY
Female Rats: No Evidence
Type Organ/Tissue (Lesion)
Non-Neoplastic Lesions
  • KIDNEY: CYTOMEGALY
Male Mice: No Evidence
Female Mice: No Evidence