https://ntp.niehs.nih.gov/go/9630

Target Organs and Levels of Evidence for TR-295

Toxicology and Carcinogenesis Studies of Chrysotile Asbestos (CASRN 12001-29-5) in F344/N Rats (Feed Studies)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Asbestos, chrysotile(IR)
12001-29-5
07/27/1984 Dosed-Feed
0,1 %/250 PER GROUP
National Institute of Env. Health Sciences

Levels of Evidence

Male Rats: Some Evidence
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Intestines: ADENOMATOUS POLYP 0/85 9/250 2/100
 

 
Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Asbestos, chrysotile(IR)
12001-29-5
07/27/1984 Dosed-Feed
0,1% /250 PER GROUP
Hazleton, Vienna

Levels of Evidence

Female Rats: No Evidence
 
Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Asbestos, chrysotile(IR) + Dimethyl hydrazine
12001-29-5
07/27/1984 Dosed-Feed
0,1 %/175 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Inadequate Study
Female Rats: Inadequate Study

 
Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Asbestos, chrysotile(SR)
12001-29-5
07/27/1984 Dosed-Feed
0,1 %/250 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: No Evidence
Female Rats: No Evidence