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Target Organs and Levels of Evidence for TR-314

Toxicology and Carcinogenesis Studies of Methyl Methacrylate (CASRN 80-62-6) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Methyl methacrylate
80-62-6
12/09/1985 Inhalation
FR: 0,250,500, MR&M: 0,500,1000 PPM/50 PER GROUP
Battelle Northwest Laboratory

Levels of Evidence

Male Rats: No Evidence
Type Organ/Tissue (Lesion)
Non-Neoplastic Lesions
  • NASAL CAVITY: INFLAMMATION; DEGENERATION, EPITHELIAL
Female Rats: No Evidence
Type Organ/Tissue (Lesion)
Non-Neoplastic Lesions
  • NASAL CAVITY: INFLAMMATION; DEGENERATION, EPITHELIAL
Male Mice: No Evidence
Type Organ/Tissue (Lesion)
Non-Neoplastic Lesions
  • NASAL CAVITY: INFLAMMATION; DEGENERATION, EPITHELIAL; HYPERPLASIA, EPITHELIAL
Female Mice: No Evidence
Type Organ/Tissue (Lesion)
Non-Neoplastic Lesions
  • NASAL CAVITY: INFLAMMATION; DEGENERATION, EPITHELIAL; HYPERPLASIA, EPITHELIAL