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https://ntp.niehs.nih.gov/go/12499

Rotenone: Target Organs and Levels of Evidence for TR-320

Toxicology and Carcinogenesis Studies of Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Chemical (Study Title)
CASRN		Peer Review DateRoute/Exposure LevelsStudy Laboratory
Rotenone
83-79-4		08/19/1986Dosed-Feed
R: 0, 38, OR 75 PPM M: 0, 600, OR 1200 PPM; 50 PER GROUP		Battelle Columbus Laboratory

Levels of Evidence

Male Rats: Equivocal Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Parathyroid Gland: ADENOMA 1/41 0/44 4/44
Female Rats: No Evidence
Male Mice: No Evidence
Female Mice: No Evidence