Skip to Main Navigation
Skip to Page Content

COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/13744

2-Amino-5-nitrophenol: Target Organs and Levels of Evidence for TR-334

Toxicology and Carcinogenesis Studies of 2-Amino-5-Nitrophenol (CASRN 121-88-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review DateRoute/Exposure LevelsStudy Laboratory
2-Amino-5-nitrophenol
121-88-0
03/04/1987Gavage
R: 0,100,200, M: 0,400,800 MG/KG/50 PER GROUP
Physiological Research Laboratory

Levels of Evidence

Male Rats: Some Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Pancreas Acinar Cell: ADENOMA 1/50 10/50 3/49
May Have Been Related
  • Preputial Gland: ADENOMA 3/50 2/50 1/50 OR CARCINOMA 0/50 0/50 4/50 COMBINED 3/50 2/50 5/50
Female Rats: No Evidence
TypeOrgan/Tissue (Lesion)
May Have Been Related
  • Clitoral Gland: ADENOMA 2/50 1/50 7/50 OR CARCINOMA 1/50 2/50 0/50 COMBINED 3/50 3/50 7/50
Male Mice: No Evidence
Female Mice: No Evidence